Suneil Koliwad, MD, PhD, and his team have discovered a new biological pathway in fat cells that could explain why some people with obesity are at high risk for metabolic diseases such as type 2 diabetes. The new findings – demonstrated initially in mice and supported by data from human patients – could lead to new biomarkers to predict who is at risk and guide treatments to reduce the medical burden of obesity.

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The American Diabetes Association recently issued revised diabetes screening guidelines for Asian Americans. To view a brief video about the guidelines, please click the following link.

In a study published June 5, 2017, in Cell Metabolism, Suneil Koliwad, MD, PhD, the Gerold Grodsky, PhD/JAB Chair in Diabetes Research, reported his team’s findings that immune cells in the brain may trigger overeating and weight gain in response to diets rich in fat.

According to Dr. Koliwad, these immune cells may “represent an untapped and completely novel way to target the brain in order to potentially mitigate obesity and its health consequences,” including type 2 diabetes.