Publications

2017

Valdearcos M, Douglass JD, Robblee MM, Dorfman MD, Stifler DR, Bennett ML, Gerritse I, Fasnacht R, Barres BA, Thaler JP, Koliwad SK. Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metab. 2017 Jul 5;26(1):185-197.e3. doi: 10.1016/j.cmet.2017.05.015.

Feng X, Valdearcos M, Uchida Y, Lutrin D, Maze M, Koliwad SK. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. JCI Insight. 2017 Apr 6;2(7):e91229. doi: 10.1172/jci.insight.91229.

2016

Azar KM, Koliwad S, Poon T, Xiao L, Lv N, Griggs R, Ma J. The Electronic CardioMetabolic Program (eCMP) for Patients With Cardiometabolic Risk: A Randomized Controlled Trial. J Med Internet Res. 2016 May 27;18(5):e134. 

Vujic N, Porter Abate J, Schlager S, David T, Kratky D, Koliwad SK. Acyl-CoA:Diacylglycerol Acyltransferase 1 Expression Level in the Hematopoietic Compartment Impacts Inflammation in the Vascular Plaques of Atherosclerotic Mice. PLoS One. 2016 May 25;11(5):e0156364. 

Robblee MM, Kim CC, Porter Abate J, Valdearcos M, Sandlund KL, Shenoy MK, Volmer R, Iwawaki T, Koliwad SK. Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells. Cell Rep. 2016 Mar 22;14(11):2611-23. 

Herman, W.H., Donner, T.W., Dudl, R.J., Florez, H.J., Fradkin, J.E., Hayes, C.A., Kalyani, R.R., Koliwad, S.K., et al, for the Writing Group of The Professional Practice Committee of the American Diabetes Association. Standards of Medical Care in Diabetes - 2016. 2016. Diabetes Care, 39(1). PMID: 26696673.

2015

Rottkamp DM, Rudenko IA, Maier MT, Roshanbin S, Yulyaningsih E, Perez L, Valdearcos M, Chua S, Koliwad SK, Xu AW. Leptin potentiates astrogenesis in the developing hypothalamus. Mol Metab. 2015 Sep 4;4(11):881-9. doi: 10.1016/j.molmet.2015.08.005. eCollection 2015 Nov.

Valdearcos M, Xu AW, Koliwad SK. Hypothalamic inflammation in the control of metabolic function. Annu Rev Physiol. 2015;77:131-60. doi: 10.1146/annurev-physiol-021014-071656. Review.

Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology. 2015 Jan;61(1):141-52. doi: 10.1002/hep.27379. Epub 2014 Nov 24.

2014

Valdearcos M, Robblee MM, Benjamin DI, Nomura DK, Xu AW, Koliwad SK. Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function. Cell Rep. 2014 Dec 24;9(6):2124-38. doi: 10.1016/j.celrep.2014.11.018. Epub 2014 Dec 11.

2013

Warne JP, Varonin JM, Nielsen SS, Olofsson LE, Kaelin CB, Chua S Jr, Barsh GS, Koliwad SK, Xu AW. Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein. J Neurosci. 2013 Jul 17;33(29):11972-85. doi: 10.1523/JNEUROSCI.0830-13.2013. 

2012
Gray, N. E., Lam, L. N., Yang, K., Zhou, A. Y., Koliwad, S.*, & Wang, J. C.* (2012). Angiopoietin-like 4 (Angptl4) Protein Is a Physiological Mediator of Intracellular Lipolysis in Murine Adipocytes. Journal of Biological Chemistry, 287(11), 8444–8456. doi:10.1074/jbc.M111.294124 *Corresponding authors
 
 
2010
Koliwad, SK, Streeper, RS, Monetti, M, Chan, L, Rao, M, Terayama, K, Naylor, S, Marmor, S, Hubbard, B, and Farese, RV, Jr. (2010) DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced inflammation and insulin resistance. J. Clin. Invest. 120(3): 756-767.
 
2009
Koliwad, SK, Kuo, T, Shipp, LE, Backhed, F, So, AY-L, Gordon J, Farese, RV Jr, Yamamoto, and Wang, J-C. (2009) Fasting-induced Adipose Factor/Angiopoietin-like 4 (FIAF/ANGPTL4) is a Glucocorticoid Receptor Primary Target Gene Involved in Glucocorticoid-regulated Triglyceride Metabolism. J Biol Chem. 284(38):25593-601.
 
2008
Yen, C-L., Stone, SJ, Koliwad, SK, Harris, CH, and Farese, RV, Jr. (2008) DGAT enzymes and triacylglycerol biosynthesis. J. Lipid Res. 49(11):2283-301.
 
2006
Streeper, RS, Koliwad, SK, Villanueva, C, and Farese, RV, Jr. (2006) DGAT1-deficiency protects from diabetes and obesity by a mechanism independent of adiponectin. Am. J. Physiol Endo Metab. 291(2):E388-94.